The GenitoUrinary Development Molecular Anatomy Project (GUDMAP) provides data and tools
that facilitate research on the GenitoUrinary (GU) tract for the scientific and medical community.
Who We Are
Since its inception, GUDMAP has focused on the kidney, lower urinary tract and nociceptors (pain receptors) and associated cell types in pain processing of the urinary tract and pelvic region.
The GenitoUrinary Development Molecular Anatomy Project (GUDMAP) is a consortium of laboratories working to provide the scientific and medical community with curated data and tools to facilitate research on the GenitoUrinary (GU) tract. The key components are:
- a molecular atlas of gene expression for the developing and mature organs of the human and mouse GU tract;
- a high resolution molecular anatomy that highlights development of the GU system;
- mouse strains to facilitate developmental and functional studies within the GU system;
- tutorials describing GU organogenesis and innervation; and
- access to consortium generated data, unpublished and published, via the ATLAS-D2K data repository.
The main focus of the current GUDMAP4 phase is [expanding our understanding of human development of the genito-urinary system.]
The GUDMAP tools, tutorials and database are a public resource funded by the National Institutes of Health, USA.
Tutorials View all
GUDMAP Publications
- Single-cell and spatial mapping identify cell types and signaling networks in the human ureter (Dev Cell, August 2022)
- Single cell transcriptomic analysis of external genitalia reveals complex and sexually dimorphic cell populations in the early genital tubercle (Dev Bio, September 2021)
- Altered sacral neural crest development in Pax3 spina bifida mutants underlies deficits of bladder innervation and function (Dev Bio, August 2021)
- 5-HT3 Signaling Alters Development of Sacral Neural Crest Derivatives That Innervate the Lower Urinary Tract (International Journal of Molecular Sciences, June 2021)
